LEUCEMIE MYELOIDE CHRONIQUE PDF

Évaluation de l’imatinib dans la prise en charge de la leucémie myéloïde chronique au Gabon À propos de dix-sept cas Volume 26, numéro 2, Avril-Mai- Juin. REVUE MEDICALE DE LIEGE. Cliquer ICI pour déclencher le téléchargement de l’article. COMMENT JE TRAITE LA LEUCEMIE MYELOIDE CHRONIQUE. Résumé La leucémie myéloïde chronique (LMC) est un modèle de cancérogenèse. Son pronostic a été exceptionnellement amélioré grâce.

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Leucémie myéloïde chronique (LMC) · Groupe québécois de recherche en LMC-NMP

Tyrosine kinase inhibitor TKI therapy imatinib, dasatinib, nilotinib, bosutinib, ponatinib has led to improved overall and disease-free survival of patients. New technologies myelide PCR, high-throughput sequencing or NGS were developed to improve the performances of existing methods. International recommendations facilitate the management of CML and treatment adjustments.

Clinical trials have validated TKI discontinuation strategies in patients with sustained deep molecular response. For the remaining half of patients, the causes leading to the molecular relapse deserve to be further analyzed. The persistence of TKI-refractory leukemic stem cells could explain this result.

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New strategies to eradicate these residual cells by targeting the hematopoietic niche or directly the leukemic stem cells are being developed. Finally, the immune system undoubtedly plays a crucial function in the control of residual leukemic cells; this role should be specified in the future. Journal page Archives Contents list. Access to the text HTML. Access to the PDF text.

RMLG – ACCES A L’ARTICLE :COMMENT JE TRAITE LA LEUCEMIE MYELOIDE CHRONIQUE (LMC).

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Leucémie myéloïde chronique (LMC)

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