changes in IBDQ score and changes in other mea- sures were similar. We conclude that although fur- ther testing is required, particularly in examining. original IBDQ which was 32 items. Measures quality Harvey Bradshaw Index ( HBI) uses a 1-day score for signs and symptoms and is not weighted. Correlates . Conclusions: Scores of the IBDQ equal or superior to suggest quality of life comparable to that perceived by the general population. This study allowed to .

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J Gastroenterol Hepatol ; One such precaution is greater emphasis on stress management. Health-related quality of life in inflammatory bowel disease. A simple index of Crohn’s Disease activity. All the patients taking part in this study filled in two quality of life questionnaires: The impact of epidemiological and disease-specific characteristics on IBDQ was studied.

The patients’ HRQoL was assessed using specific and generic questionnaires. Email alerts New issue alert. Given the disproportionately small number of men in this study, the results herein should not be generalized to men unless validated by larger studies with a more proportionate gender ratio.

The Mayo score and the partial Mayo score are commonly used disease activity indices in placebo-controlled trials in UC. Inflammtory bowel disease in the elderly. Disease-specific knowledge, coping, and adherence in patients with inflammatory bowel disease. Sainsbury A, Heatley RV. However, past studies have found that patient knowledge about chronic illness has been effective in reducing anxiety and perceived stress and may potentially improve health-related quality of life and symptoms of depression.

In a large cohort of UC and CD patients from 20 European centres EC-IBD Study a similar clinical course during the first year after manifestation of the disease was found in young and older patients [ 5051 ].


Anna Oliveras for valuable contributions to the English revision of this manuscript. Pallis AG et al [12] demonstrated results consistent with ours, reporting disease activity as the major variable affecting QoL, whereas age, smoking, type of disease CD or UC and disease duration had no impact.

Firstly, the cross-sectional design and the small population size, secondly, most patients received combined medication and thus, there is a risk of bias on the impact of different treatment regimens on HRQoL, and lastly, the vast majority of our patients had disease in remission.

This is an important observation leading to the conclusion that, at least in Greek IBD patients, disease activity plays a major role in their perception of quality of life. Except where otherwise noted, this work is distributed under the terms of a Creative Commons Attribution-NonCommercial- NoDerivatives 4. Disease activity, behavioral dysfunction, and health-related quality of life in adolescents with inflammatory bowel disease.

Tabibian; Health-related quality of life in inflammatory bowel disease: Please review our privacy policy. A Review of Emerging Themes. As shown in Fig. The proportion of females in the UC group All the patients completed two HRQoL questionnaires: Univariate analyses of all the psychosocial, clinical, and demographic variables revealed several significant associations.

This is essentially in agreement with past work, wherein one of the most important HRQOL determinant for patients with IBD was the presence of disease activity.

Among all variables recorded in our study, only disease activity scoree a significant effect on HRQoL. Sign In or Create an Account. This study also reproduced the prior finding of lower HRQOL in women as compared to men with IBD, 91038 although this should be interpreted with caution as the majority sckre individuals in this study were women.

Cigarette smoking in Crohn’s disease.

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Such an approach may result into a better understanding of the patients’ global situation and the many difficulties they experience due to their disease. Jaghult et al [9] reported that patients with longer disease duration have better HRQoL than patients with short duration and also that this correlation may be due to the fact scroe the disease tends to be more active at first appearance [] or that the patient may have not as yet been treated adequately.


The influence of demographic and disease-related factors on health-related quality of life in patients with ulcerative colitis. Demographic and disease-related data were recorded. Multivariate regression analyses between predictor variables and IBDQ scores. Transplantation of Human Intestine into the Mouse: Strategies to Improve quality of life in adolescents with inflammatory bowel disease. Patients were classified according age at the time of diagnosis into two groups; those who were less than 60 indq old and those who were equal or older than 60 years.

VALIDITY OF OUTCOME MEASURES – Golimumab (Simponi) (Subcutaneous Injection) – NCBI Bookshelf

The demographic characteristics of the study population are shown in Table 1. Mild, moderate, and severe disease activities are indicated by score ranges of 3 to 5 points, 6 to 10 points, and 11 to 12 points, respectively. Patients in our study using the same instrument scored higher than previously reported. Our study shares similar results with the study by Han et al [ 22 ], while DeBoer et al found significantly lower scores [ 19 ].

The SF health survey questionnaire: