Not to be confused with sixth disease. See Exanthema subitum. Erythema infectiosum or fifth disease is one of several possible manifestations of infection by. Erythema infectiosum (fifth disease). Erythema infectiosum is a mild childhood disease that is caused by human parvovirus B This condition. A general overview of the symptoms, causes and treatment of fifth disease, and other useful tips for parents.

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Most people become immune to the virus after having it once. Erythema infectiosum is a common viral exanthem illness found in children.

To access free multiple choice questions on this topic, click here. Call your doctor if you or your child develops a facial rash, especially if your child has ertyhema blood disorder or an immune deficiency, or is being treated for cancer.

In patients who are immunocompromised or in patients with hematologic disorders, symptoms can be more severe. Home care for a child whose rash itches may diisease oatmeal baths or other over-the-counter bath treatments. The virus itself, or its viral DNA genetic mapalso can be detected in the blood of some patients. It was better defined by Anton Tschamer in as a rubella variant Ortliche Rothelnidentified as a distinct condition in by Theodor Escherichand given the name “erythema infectiosum” in These joint symptoms typically resolve after about 3 weeks of symptom onset.


This page was last edited on 19 Decemberat Incubation and contagion periods:. The reticular rash is often present more on the extensor surfaces.

Erythema, Infectiosum (Fifth Disease) – StatPearls – NCBI Bookshelf

Fifth disease spreads easily, through saliva and mucus. Clinical heterogeneity of human parvovirus B19 infection following adult liver This rash does not develop early in the disease process.

Show details Treasure Island FL: Days after the facial rash develops, a maculopapular rash eryfhema develops on the trunk and limbs. Quantitation of human parvovirus B19 DNA in erythema infectiosum and aplastic crisis.

Please review our privacy policy. This rash is thought to be immune-mediated. No specific therapy is recommended. Review Clinical presentations of parvovirus B19 infection.

Fifth Disease (Erythema Infectiosum)

The disease is usually mild, [4] but in certain risk groups, it can have serious consequences:. Acute infection and exposure to a fetus can be fatal.

Parvovirus B19 infects humans only and is not the same as nifectiosum parvovirus that infects dogs. Infected children and adults will be contagious from as much as seven days before and right up to the moment the characteristic rash may appear.

Fifth disease

Fifth disease, also known as erythema infectiosum, is a common viral infection among school-aged children. Available for Android and iOS devices.

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Subscribe to receive email notifications whenever new articles are published. The blotchy rash may itch, and it may last from several days to several weeks before it fades.

Infection by parvovirus B19 destroys reticulocytes. Usually, your doctor can diagnose fifth disease by seeing the typical “slapped cheek” rash without fever or other signs of illness.

Fifth disease – Wikipedia

When joint symptoms are present, the patient is not considered infectious or contagious. Adolescents and adults with fifth disease may not have infectuosum symptoms or they may develop the typical rash, joint pain and swelling most often at the knuckles, wrists and knees or both.

It more commonly occurs in school-age children who are 5 to 15 years old. Pathophysiology Parvovirus B19 is transmitted most commonly through respiratory droplets into cells in the respiratory tract.

These symptoms pass, then a few days later, the rash appears. In addition, pregnant women who contract the virus may pass the infection to the fetus in some cases.