Antidysrhythmic agents, which are also known as antiarrhythmic agents, are a broad category of medications that help ameliorate the spectrum of cardiac. The ultimate goal of antiarrhythmic drug therapy is to restore normal rhythm and conduction. When it is not possible to revert to normal sinus rhythm, drugs may. Antidysrhythmic Drugs: Amiodarone, Digoxin, Disopyramide, Flecainide, Lidocaine, Procainamide, Quinidine answers are found in the Davis’s Lab & Diagnostic.

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It is, therefore, not a true classification in that it does not aggregate drugs into categories.

Class III agents predominantly block the potassium channelsthereby prolonging repolarization. It presents the drugs on two axes, instead of one, and is presented antiydsrhythmic tabular form. Class IV agents include verapamil and diltiazem. The result is an expanded but pragmatic classification that encompasses approved and potential anti-arrhythmic drugs.

A new approach to the classification of antiarrhythmic drugs based on their actions on arrhythmogenic mechanisms. Druga site uses cookies. Wikipedia articles needing page number citations from January All articles with dead external links Articles with dead external links from November Wikipedia articles with NDL identifiers.

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There are four classes of antidysrhytmics which each have a different mechanism of action. Please enter Password Forgot Username? Pharmacology for dgugs ver. View Table Favorite Table Download. Antiarrhythmic drugs are used to:.


Vaughan Williams Classification of Antidysrhythmic Drugs

Class IA drugs quinidine, procainamide, and disopyramide prolong the repolarization and the refractoriness of isolated myocardial tissue as well as block the inward sodium current. This site uses cookies to provide, maintain and improve your experience.

A recent publication has now emerged with a fully modernised drug classification. Calcium channel blockers and beta-blockers are useful for this indication. Lidocaine Phenytoin Mexiletine Tocainide.

Antidysrhythmic drugs are used to treat dysrthythmias, which is any deviation from the normal rhythm of the heart. By using antidysrhytbmic site, you agree to the Terms of Use and Privacy Policy. Those proposed in were: Digitalis, because of its ability to sntidysrhythmic the vagus nerve parasympathomimetic effectcan also be used to reduce AV conduction velocity in an attempt to normalize ventricular rate during atrial flutter or fibrillation.

On the Y axis, each drug is listed, in roughly the Singh-Vaughan Williams order. Use this site remotely Bookmark your favorite content Track your self-assessment progress and more! Beta blocking Antidsyrhythmic also shows some class I action.

Interactions Are unique to each individual drug but can include the potentiation of anticoagulent activity with warfarin coumadin.

Antidysrhythmic Drugs | Student of Nursing Blog

It starts by considering the range of pharmacological targets, and tracks these to their particular cellular electrophysiological effects. Because beta-adrenoceptors are coupled to ion channels through defined signal transduction pathwaysbeta-blockers indirectly alter membrane ion conductance, particularly calcium and potassium conductance. Many attempts have been made to classify antiarrhythmic agents. Search within a content type, and even narrow to one or more resources.


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From Wikipedia, the free encyclopedia. Common adverse effects include hypersensitivity reactions, nausea, vomiting, diarrhea, dizziness, headache and blurred vision. Used in supraventricular arrhythmias, especially in heart failure with atrial fibrillation, contraindicated in ventricular arrhythmias. The problem arises from the fact that many of the antiarrhythmic agents have multiple modes of action, making any classification imprecise.

Drugs that block slow inward druga channels are used to reduce pacemaker firing rate by slowing the rate of rise of depolarizing pacemaker potentials phase 4 depolarization. Ventricular arrhythmias Prevention of paroxysmal recurrent atrial fibrillation triggered by vagal overactivity Procainamide in Wolff-Parkinson-White syndrome Increases Drusg interval. These materials are for educational purposes only, and are not a source of medical decision-making advice.

Antidotes Contrast media Radiopharmaceuticals Dressings Senotherapeutics.

Antiarrhythmic agent – Wikipedia

They decrease conduction through the AV node. Sometimes ventricular rate is excessively high because it is being driven by atrial flutter or fibrillation. Anticancer agents Antimetabolites Alkylating Spindle poisons Antineoplastic Topoisomerase inhibitors.

Decreasing conduction velocity can help to abolish tachyarrhythmias caused by reentry circuits. Freeman, and Jeffrey S. Home Books Anesthesiology Core Review: Class IV agents are slow non-dihydropyridine calcium channel blockers.

Abnormal impulse generation falls into one of two categories: