Amphipterygium adstringens is a plant widely used in Mexican traditional medicine for its known anti-inflammatory and antiulcer properties. Amphipterygium adstringens is a deciduous shrub or small tree, commonly growing about 3 – 6 metres tall, with a broad and rather flat or sometimes narrow . PDF | Extracts from the bark of Amphipterygium adstringens, known as Cuachalalate, is in Mexico commonly used to treat several gastrointestinal disorders.

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Oxidative stress is one of the most crucial factors causing UC.

Principles of the bark of Amphipterygium adstringens (Julianaceae) with anti-inflammatory activity.

Compared adshringens control mice, DSS mice showed significantly increased histopathological scoring of disease Figure 3 a. National Center for Biotechnology InformationU. The male flower is actinomorphic.

Evidence-Based Complementary and Alternative Medicine. In this grading system, inflammation severity was scored on a 0—3 scale 0: Table of Contents Alerts. Therefore, better therapeutic agents that effectively attenuate mucosal inflammation with minimum or no side effects are needed.

Food and Chemical Toxicology. In vitro antioxidant tests using free radical traps are relatively straightforward to perform.

However, the fact that IL levels did not show significant changes in our experiments is indicative that downmodulation of the inflammatory response by AaEE treatment is not associated with IL levels and perhaps some of the compounds identified in our extracts of A. These leaflets have a cuneate base and an obtuse or rounded apex, its margin is dentate or crenate. Whole plant and bark of Amphipterygium adstringens growing in Michoacan, Mexico.


Strains were cultured following their specific requirements. The Folin-Ciocalteu method [ 22 ] was used to determine the total phenolic content of a 0.

For example, the chemical structure of catechin consists of a polyphenolic ring condensed with six-member oxygen containing heterocyclic ring that carries another polyphenolic ring. Its branches are usually covered with scars of fallen leaves and may be bare or covered with fine hair-like structures. The colon length was Antioxidant, antimicrobial and cytotoxic activities of selected medicinal plants from Yemen.

It is presented by a variety of clinical manifestations, including attacks of abdominal cramps, pain, bloody diarrhea, bleed per rectum, weight loss, fever, and easy fatigability, which may begin gradually or start totally all at once [ 12 ].

Antioxidant activity and phenolic compounds in selected herbs. Long-chain phenols from the bark adstringnes Amphypterygium adstringens. Assessment included noting of edema, extent of injury, leukocyte infiltration, crypt abscesses, and loss of goblet cells.

These phytochemicals compounds of AaEE have been found adstrlngens induce a wide spectrum of activities such as reduction in oxidative stress, suppression of inflammation, and cell proliferation and modulating numerous signal transduction pathways. The supernatant was collected for the biochemical estimations. Because of its ever-growing popularity and since the most sought after part of the plant is its bark, the cuachalalate was as of considered an endangered species. Support Center Support Center.

Amphipterygium adstringens – Wikipedia

Therefore, our findings indicate that AaEE treatment of colitis might be reducing the extent of colonic injury by its antioxidant ability. With respect to IL, this cytokine contributes to the differentiation of regulatory T cells Treg addtringens, while suppressing dendritic cell-associated Th1 and Th17 immunity, as well as regulating inflammatory responses [ 3637 ]. European Journal of Pharmacology.


View at Google Scholar A.

Amphipterygium adstringens is a plant widely used in Mexican traditional medicine for its known anti-inflammatory and antiulcer properties. Our observations are in agreement with those reported in other studies using the DSS-induced colitis model [ 226 ]. Mauricio Gonzalez, following the last revision of the genus Amphipterygium Julianaceae [ 46 ].

The stamen is amphipterygiim, with a filament averaging at only. Ulcerative colitis UC is a major type of inflammatory bowel disease characterized by chronic, relapsing intestinal inflammation with extensive damage of colonic mucosa. This is an open access article distributed under the Creative Commons Attribution Licensewhich permits unrestricted adstringenss, distribution, and reproduction in any medium, provided the original work is properly cited. In this investigation, we tested the crude extract of A.

Crude extract CE of A. Use of medicinal plants in Monterrey, Mexico.

Amphipterygium adstringens

Preparations and formulations of this CE can be improved and applied for daily use in dental products to prevent caries and periodontal diseases and concomitantly weaken adetringens risk of cancer. The weight loss, stool formation, and bloody stool scores were averaged to determine the DAI.

View adstrigens Google Scholar J. Cytotoxic activity and effect on nitric oxide production of tirucallane-type triterpenes. On the other hand, inflammatory responses play a critical role in the pathogenesis of UC.