Part, Category. Description, 4-bit Shift Register. Company, ETC. Datasheet, Download datasheet. Quote. Find where to buy. Quote. # Store at. °C. 5-Formylcytosine (5-fC) (D5D4K) Rabbit mAb . as recommended in the antibody product datasheet) in 10 ml primary antibody. Datasheet PDF Download – 4-Bit Shift Register, data sheet.
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Datasheet PDF – ETC1
(PDF) Datasheet PDF Download – 4-Bit Shift Register
While 5-fC and 5-caC appear to be short-lived intermediate species, there is mounting evidence showing that 5-hmC is a distinct epigenetic mark with various unique functions 10, Please let us know! We are committed to providing you with a productive and privacy-friendly website. We wish you a successful ! The antibody was titrated against a single-stranded DNA oligo containing either unmodified cytosine or differentially modified cytosine 5-mC, 5-hmC, 5-caC, 5-fC.
The upper panel shows the antibody only binding to the DNA fragment containing 5-fC, while the lower panel shows the membrane stained with methylene blue.
Please change your password to something memorable and secure upon logging in. Our website shows product prices without login! If so we’d love to hear about it. Login No need to login to view prices! Your credentials are incorrect or you are trying to login with a non-existing webshop account. Have trouble resetting your password? By proceeding on datasheeh website, you agree to the placement of these cookies. Additionally, TET proteins can further oxidize 5-hmC to form 5-formylcytosine 5-fC and 5-carboxylcytosine 5-caCboth of which are excised by thymine-DNA glycosylase TDGeffectively linking cytosine oxidation to the base excision repair pathway and supporting active cytosine demethylation 6,7.
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Therefore 744178 accounts that were only used to view prices have been deleted. The global level of 5-hmC increases during brain development, and 5-hmC is enriched datashete promoter regions and poised enhancers.
This product is intended for research purposes only. Since then this modification has been discovered in many tissues, with the highest levels found in the brain 9. The same sequence of a base pair DNA fatasheet was generated by PCR using exclusively unmodified cytosine, 5-methylcytosine 5-mC5-hydroxymethylcytosine 5-hmC5-carboxylcytosine 5-caCor 5-formylcytosine 5-fC.
Lower amounts of 5-hmC have been reported in various cancers including myeloid leukemia and melanoma 13, The modified base itself is stable in vivo and interacts with various readers including MeCP2 11, Datasheet Datasheet CST Have you published research involving the use of our products?
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Find your product Go. Furthermore, there is an inverse correlation between levels of 5-hmC and histone H3K9 and H3K27 trimethylation, suggesting a role for 5-hmC in gene activation